The Top 15 Best Vitamin C Supplements of 2022

Vitamin C is considered nature’s best antioxidant. Over the years, vitamin C supplements have gained substantial popularity, and many people take these supplements to target inflammation and overall health. Vitamin C products come in different forms, including capsules, skin creams, and serums.

Vitamin C plays a vital role in improving your health – and no wonder a diet that contains vegetables and fruits (having vitamin C) is considered a rich diet. Also, the best part is that your body’s vitamin C absorption remains the same whether you take it as a supplement or a food.

Today, you can find numerous vitamin C supplements on the market claiming to provide fantastic benefits. However, not all of them live up to their claim. After extensive research, our team of experts has selected the best vitamin supplements worth buying in 2022.

The Top Vitamin Supplements in 2022

According to our experts, the following are the top vitamin C supplements you should consider buying in 2022:

  • Micelle Liposomal Radiant
  • Nano C
  • Optimunity
  • Restore Vitamin C Serum
  • Essential C Complex
  • Pure Neuro
  • Liposomal Synergy C
  • CitruSlim
  • Rootine
  • Vitamin C by Amazon Elements
  • Vitamin C by Life Extension
  • Revolution-C
  • Liposomal Vitamin C (Dr. Mercola)
  • Lypo-Spheric Vitamin C
  • Immune Gummies

Micelle Liposomal Radiant


If you’re looking for a vitamin C supplement to provide potent antioxidant effects with optimal absorption of vitamin C, look no further than Micelle Liposomal Radiant. This supplement promotes healthy aging, supports skin, and enhances nail and hair appearance.

Each supplement serving contains 0.035oz of vitamin C to maximize antioxidant effects. The best thing about this formula is that it uses micelle liposomal technology to allow vitamin C to travel through your digestive system safely. This way, it helps your body absorb vitamin C more efficiently. Overall, this supplement is one of the best on the market.

Nano C


One of the top-rated brands in the vitamin C supplement space, Zenith Labs formulates this top-notch supplement. You can boost your immune function, combat colds and other viruses rapidly, and prevent infections by taking this supplement daily.

The manufacturers claim that Nano C is their most popular vitamin C product. They have named it Nano C since they have used nano-sized particles, making them easy to absorb.

While other formulas on our list use a simple dose of vitamin C, this supplement tends to provide your body with vitamin C in 30x smaller portions than other vitamin C supplements. This can maximize the absorption of vitamin C. On top of that, Nano C is a doctor-formulated supplement by Dr. Ryan Shelton.



This is one of the well-rated vitamin C supplements on the market. Each serving contains 0.052oz of vitamin C. You can optimize the absorption of vitamin C and boost your immune system by taking this supplement daily.

In addition, you can protect your body from fevers, flu, viruses, and other harmful diseases.

According to the manufacturers, other vital benefits of Optimunity include:

  • It boosts energy levels
  • It reduces the risk of stroke
  • It promotes healthy skin aging
  • It prevents iron deficiency
  • It stops gout attacks

This formula promotes your overall wellness by providing potent antioxidant effects of vitamin C.

Restore Vitamin C Serum


This is one of the most popular vitamin C supplements formulated to reduce wrinkles and repair skin. Though this is one of the most expensive formulas on our list, it’s one of the few that contains a blend of hyaluronic acid and vitamin C.

By combining vitamin C and hyaluronic acid, this supplement aims to support your skin health in multiple ways. You need to apply a few drops of this supplement once daily after cleansing your skin. Also, make sure you use this serum before applying moisturizer. Once you’ve applied the drops, gently massage the oil into your skin and neck.

Essential C Complex


This high-profile vitamin C supplement by Paleovalley aims to boost your immunity while enhancing your overall health. This supplement stands out among other vitamin C supplements on our list because it combines a full-spectrum vitamin C with organic superfoods.

These antioxidant-rich superfoods include:

  • Camu Camu berry
  • Acerola cherry
  • Amla berry

These three superfoods are some of the best sources of vitamin C. On top of that, each serving of Essential C Complex contains a good quantity of vitamin C to boost your daily intake.

Pure Neuro


PureLife Organics, one of the best brands in the supplement space, formulates this top-rated formula that targets brain optimization. This is the only supplement on our list explicitly designed to enhance brain power instead of the immune system or skin health.

Studies suggest that antioxidants like vitamin C can boost brain power, cognitive energy, and overall brain health – and that is Pure Neuro’s primary focus.

This supplement is also unique because Dr. Anthony Capasso formulates it. He made this supplement to protect your brain from everyday toxins, anxiety, stress, and other radiations. According to Capasso, you can support your brain’s power cells and enhance your memory by taking this supplement daily.

Liposomal Synergy C


If you’re looking for a top-notch vitamin C supplement to boost your immune system, improve collagen production, and promote healthy aging, Synergy C will be ideal.

This supplement contains a blend of vitamin C with high-profile, active ingredients as protective fatty molecules. This makes it easy for your body to absorb the maximum vitamin C.

By taking this supplement daily, you can provide your body with 0.035oz of vitamin C. With a potent dosage of vitamin C, high-class ingredients, and fantastic results, Liposomal Synergy C is one of the best supplements to buy in 2022.



While most vitamin C supplements on our list target the immune system or skin health, CitruSlim is the only formula that supports weight loss by reducing hunger. As the name suggests, this supplement contains a blend of citrus extracts and other active ingredients.

This supplement claims to control hormones associated with your satiety and hunger so that you eat less. Other benefits you can get from this supplement include:

  • It helps maintain a balanced cortisol response to stress
  • It accelerates your weight loss process
  • It supports your cardiovascular function
  • When it comes to ingredients, CitruSlim contains the following:
  • Eurycoma Longifolia root extract
  • Bergamot fruit extract
  • Glycol saponins
  • Bioactive eurypeptides

These ingredients combine to support weight loss in multiple ways. Overall, CitruSlim is one of the best vitamin C supplements to help lose weight.



Rootine is one of the most popular brands in the industry that provides customized vitamin C supplements and nutrition kits (personalized) according to your needs. The best thing about using this vitamin C supplement is getting a custom spectrum of vitamins catering to your unique needs.

The brand also provides an option to add a blood or DNA test to your supplement order for optimal customizability. Overall, the vitamin C supplement by Rootine is perfect for those looking to find a customized vitamin C supplement according to their unique physiology.

Vitamin C by Amazon Elements


This is one of the most popular vitamin C supplements on the internet, with numerous positive reviews and excellent ratings. This is also one of the most affordable formulas on our list, with each $20 bottle containing three hundred tablets.

You can support healthy aging and enhance your immune system by taking this supplement daily. On top of that, each tablet contains a strong dosage (0.035oz) of vitamin C. This supplement by Amazon also has one of the best ratings on our list, attaining more than eighteen thousand positive reviews and 4.8 ratings on Amazon.

Vitamin C by Life Extension


This supplement stands out among other vitamin C supplements on our list because it combines vitamin C with Bio-Quercetin Phytosome. This makes it fifty times easier to absorb than the standard version of quercetin.

This formula is also one of the most affordable vitamin C supplements on our list, with each $14 bottle containing 250 tablets. In addition, each formula serving contains 0.035oz of vitamin C.

It’s no secret that the price tag is one of the significant reasons this supplement competes with the vitamin C supplement by Amazon Elements. However, this formula uses quercetin, sourced from sunflower extract, one of the best antioxidants. If you want a vitamin C supplement with natural ingredients to support the immune system and overall well-being, Life Extension’s vitamin C supplement will be ideal.



This top-rated vitamin C supplement is one of the go-to choices among many people. This formula contains a blend of vitamin C with a unique type of quercetin called dihydroquercetin (DHQ). This version of quercetin is formulated to complement vitamin C.

You can increase the intake of antioxidants, boost your immune system, and support your overall health by taking this supplement daily. On top of that, this formula contains black pepper extract that we don’t see in other vitamin C supplements on our list.

Also, each serving of this supplement contains a potent dosage (0.035oz) of vitamin C, making it a high-powered formula to support immunity. With an affordable price tag, top-notch ingredients, concentrated dosages, and excellent effects, Revolution-C is one of the best in the business.

Liposomal Vitamin C (Dr. Mercola)


This elite vitamin C supplement is formulated by Dr. Mercola, with each formula serving containing 0.035oz of vitamin C for optimal effects. Each bottle of this supplement contains 180 capsules (ninety servings).

Dr. Mercola has formulated this supplement as a blend of vitamin C with medium-chain triglycerides (MCTs) and sunflower extract to optimize absorption. These ingredients play a vital role in helping your body absorb a significant amount of vitamin C.

With an affordable price tag, top-quality ingredients, and doctor’s endorsement, this supplement is worth buying in 2022.

Lypo-Spheric Vitamin C


This is one of the best vitamin C supplements formulated for maximum vitamin C absorption using liposomal nano-spheres. This supplement contains vitamin C in a small size, so it is easy for your body to absorb, like other vitamin C supplements on our list.

One of the best benefits of this supplement is that it contains 0.035oz of vitamin C and 0.035oz of essential phospholipids per serving. These acids can support your heart health, which you don’t often find in other vitamin C supplements.

Overall, Lypo-Spheric ranks among the top-rated vitamin C formulas on the market with high-profile ingredients, an affordable price tag, and excellent benefits.

Immune Gummies


These vitamin C gummies are formulated by one of the most popular brands in the supplement space, called Goli. These gummies are renowned for their delicious taste and for supporting the immune system in multiple ways.

When you take these gummies daily, your body tends to get a blend of the following:

  • Vitamin C
  • Elderberry extract
  • Zinc
  • Vitamin D
  • A unique botanical mixture

Over the years, Goli has established itself as an elite apple cider vinegar and ashwagandha gummy company. Today, this brand is one of the top choices among people looking to buy top-notch vitamin C supplements at an affordable price.

Factors We Considered to Select the Best Vitamin C Supplements

Numerous vitamin C supplements are available, all claiming excellent benefits. However, not all of them live up to their hype. We considered the following factors to separate the top vitamin C supplements from the rest:

Dosage of Vitamin C

The main reason for taking a vitamin C supplement is to increase the supply of vitamin C to your body. Vitamin C is a water-soluble mineral, and your body can safely absorb excess vitamin C since it excretes additional vitamin C through urine. We preferred supplements with potent dosages (0.035oz) of vitamin C and avoided those with a low quantity of vitamin C.


The top vitamin C supplements are formulated to maximize vitamin C absorption. For instance, the vitamin C formula by Zenith Labs reduces vitamin C to smaller particles with the help of nanotechnology for maximum absorption.

Similarly, some vitamin C supplements on our list use liposomal technology to boost absorption of vitamin C. With this in mind, we prefer supplements with top-notch, unique technology to maximize absorption.

Doctor’s Formulation

Marketing teams with no medical knowledge formulate some low-priced vitamin C supplements. In contrast, genuine doctors or medical professionals make the best vitamin C supplements.

No secret that any doctor-formulated supplement has additional legitimacy, making it easier for people to buy. Therefore, we gave the edge to vitamin C supplements formulated by medical professionals.

Brand Reputation

While some brands have proven to produce top-notch vitamin C supplements for decades, others are still learning their trade. We considered brand reputation a crucial factor while selecting the top vitamin C supplements.

Refund Policy

Whether you pay $20 or $80 for a vitamin C supplement, you should get good value for money in return. The top supplements are always backed with a moneyback guarantee, allowing you to request a refund if you’re unsatisfied with the product. With this in mind, we selected supplements with a fair claim policy.

Complementary Ingredients

Though vitamin C dosage is one of the significant factors when evaluating a vitamin C supplement, we also considered complementary ingredients for our rankings. The top vitamin C supplements contain complementary ingredients (antioxidants or other minerals) to boost the effectiveness of vitamin C.

Cost and Value

It’s no secret that formulating a vitamin C supplement is easy and cheap. Hence, our team conducted extensive research on the costs of various vitamin C supplements and found formulas with staggering prices. We were not biased toward a specific price point, but we selected vitamin C supplements that provide excellent benefits regardless of their cost.

Honest Advertised Benefits

According to Food and Drug Administration (FDA) regulations, supplement companies cannot market their products to treat or cure any disease. However, some vitamin C supplements still claim to eliminate health problems, while some claim to help you lose fifty pounds in a week. We selected vitamin C supplements with real advertised benefits and transparency.

10 Benefits of Vitamin C Supplements

The following are the ten benefits of vitamin C supplements:

Support Immune System

Many people use vitamin C supplements to boost their immune system since your immune system works better with vitamin C. According to experts, vitamin C supplements increase the production of white blood cells in your body and help them work more effectively.

May Handle Chronic Disease

Vitamin C supplements may reduce the risk associated with chronic disease by strengthening your body’s natural defenses.

Support Blood Pressure

Nearly thirty percent of Americans deal with high blood pressure issues. High blood pressure can lead to a heart attack. According to experts, vitamin C supplements can reduce blood pressure by relaxing your body’s blood vessels.

May Reduce The Risk of Heart Disease

It’s no secret that heart attacks are the leading cause of death around the globe. Though there isn’t any concrete evidence about it, some studies suggest vitamin C supplements can reduce the risk of heart disease.

Can Prevent Gout Attacks

Gout is formed when your body has extra uric acid. This acid forms sharp crystals in your body’s joints, particularly in the big toe, causing swelling and unbearable pain. There’s evidence that vitamin C supplements can prevent gout attacks by reducing uric acid buildup in your body.

Support Iron Absorption

Vitamin C supplements are ideal for those dealing with iron deficiency since these supplements maximize the iron absorption in your diet. Vitamin C supplements tend to convert iron that is difficult to absorb (such as plant-based iron) into a more diminutive form, making it easy for your body to absorb.

Support Cognition

It’s no secret that many people use vitamin C supplements to boost cognition and overall brain health. For instance, vitamin C supplements like Pure Neuro optimize your brain’s overall function by reducing toxins in the brain. It also reduces inflammation in the brain and boosts memory and cognition.

May Reduce the Risk of Cancer

There is significant evidence that people use vitamin C supplements to minimize cancer risk. However, all of this is subjective, with no concrete conclusions.

Support Vision

According to experts, vitamin C supplements can support your vision and protect against eye disease. Moreover, some studies suggest that these supplements may reduce the risk associated with cataracts.

Support Anti-Aging and Skin Health

One of the primary benefits of using vitamin C supplements is supporting skin health and anti-aging. Many people consume these supplements or apply drops of serum to their skin for excellent anti-aging effects. This can help make you look younger.

In addition, vitamin C supplements reduce inflammation to clear up your skin issues. These supplements also play a vital role in collagen production – the most abundant protein in your body. This is crucial since collagen supports your skin’s elasticity while preventing the formation of wrinkles.

Side Effects of Vitamin C Supplements

There is no concrete evidence that suggests vitamin C supplements have severe side effects when healthy adults take standard dosages. Even if you take high doses of vitamin C supplements, you should not experience significant side effects.

However, if you constantly take high-powered (megadoses) dosages of vitamin C, you might experience minor side effects, including:

  • Headaches
  • Nausea
  • Indigestion
  • Upset stomach

Though these side effects occur rarely, you should immediately stop taking vitamin C supplements if you continually experience such side effects. Also, one thing to note here is that if you regularly take medicine or have a health condition, it’s advisable to consult your doctor before taking a vitamin C supplement.

The Top Vitamin Supplements in 2022 Final Verdict

There’s no denying that vitamin C supplements have gained substantial growth over the years, with many people using them these days. These supplements have numerous benefits, such as boosting the immune system, reducing inflammation, supporting anti-aging, promoting healthy skin, supporting overall health, etc. Today, you can find many vitamin C supplements on the market, all claiming to use a potent dosage of vitamin C for excellent benefits. However, not all of them live up to their expectations. Consider certain factors to ensure you buy a vitamin C supplement that suits your needs. Check out the list we’ve created above if you’re looking to buy a top-notch vitamin C supplement in 2022.


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Please understand that any advice or guidelines revealed here are not even remotely substitutes for sound medical or financial advice from a licensed healthcare provider or certified financial advisor. Make sure to consult with a professional physician or financial consultant before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary and are not guaranteed as the statements regarding these products have not been evaluated by the Food and Drug Administration or Health Canada. The efficacy of these products has not been confirmed by FDA, or Health Canada approved research. These products are not intended to diagnose, treat, cure or prevent any disease and do not provide any kind of get-rich money scheme. Reviewer is not responsible for pricing inaccuracies. Check product sales page for final prices.

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